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FSHβ Polyclonal Antibody

     
  • 14 - FSHβ Polyclonal Antibody AP74092
    Immunohistochemical analysis of paraffin-embedded human-brain, antibody was diluted at 1:200
  • 14 - FSHβ Polyclonal Antibody AP74092
    Immunohistochemical analysis of paraffin-embedded human-brain, antibody was diluted at 1:200
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
IHC-P
Primary Accession P01225
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 14700 Da
Additional Information
Gene ID 2488
Other Names Follitropin subunit beta (Follicle-stimulating hormone beta subunit) (FSH-B) (FSH-beta) (Follitropin beta chain)
Dilution IHC-P~~IHC-p 1:50-200, ELISA 1:10000-20000
Format Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% (W/V) sodium azide.
Storage Conditions-20℃
Protein Information
Name FSHB
Function Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways (PubMed:24692546, PubMed:2494176). Follitropin is involved in follicle development and spermatogenesis in reproductive organs (PubMed:407105, PubMed:8220432).
Cellular Location Secreted. Note=Efficient secretion requires dimerization with CGA
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways (PubMed:2494176, PubMed:24692546). Follitropin is involved in follicle development and spermatogenesis in reproductive organs (PubMed:407105, PubMed:8220432).

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