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CTGF Polyclonal Antibody

     
  • 14 - CTGF Polyclonal Antibody AP74174
    Immunohistochemical analysis of paraffin-embedded human-skin, antibody was diluted at 1:200
  • 14 - CTGF Polyclonal Antibody AP74174
    Immunohistochemical analysis of paraffin-embedded human-lung, antibody was diluted at 1:200
  • 14 - CTGF Polyclonal Antibody AP74174
    Immunohistochemical analysis of paraffin-embedded human-lung, antibody was diluted at 1:200
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
IHC-P
Primary Accession P29279
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 38091 Da
Additional Information
Gene ID 1490
Other Names Connective tissue growth factor (CCN family member 2) (Hypertrophic chondrocyte-specific protein 24) (Insulin-like growth factor-binding protein 8) (IBP-8) (IGF-binding protein 8) (IGFBP-8)
Dilution IHC-P~~IHC-p 1:50-200, ELISA 1:10000-20000
Format Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% (W/V) sodium azide.
Storage Conditions-20℃
Protein Information
Name CCN2 (HGNC:2500)
Function Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Is involved in the stimulation of osteoblast differentiation and has a critical role in osteogenesis (PubMed:39414788). Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor- induced DNA synthesis.
Cellular Location Secreted, extracellular space, extracellular matrix {ECO:0000250|UniProtKB:P29268}. Secreted
Tissue Location Expressed in bone marrow and thymic cells. Also expressed one of two Wilms tumors tested.
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis.

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