癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
PRCC (7H14) Mouse Monoclonal antibody
PRCC (7H14) Mouse Monoclonal antibody
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- 实验流程
- 背景知识
Application 
| WB |
|---|---|
| Primary Accession | Q92733 |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Calculated MW | 52418 Da |
| Gene ID | 5546 |
|---|---|
| Other Names | Proline-rich protein PRCC, Papillary renal cell carcinoma translocation-associated gene protein, PRCC, TPRC |
| Dilution | WB~~1:1000 |
| Storage Conditions | -20℃ |
| Name | PRCC |
|---|---|
| Synonyms | TPRC |
| Function | May regulate cell cycle progression through interaction with MAD2L2. |
| Cellular Location | Nucleus. |
| Tissue Location | Ubiquitous in fetal and adult tissues. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
This gene encodes a protein that may play a role in pre-mRNA splicing. Chromosomal translocations (X;1)(p11;q21) that result in fusion of this gene to TFE3 (GeneID 7030) have been associated with papillary renal cell carcinoma. A PRCC-TFE3 fusion protein is expressed in affected carcinomas and is likely associated with altered gene transactivation. This fusion protein has also been associated with disruption of the cell cycle. [provided by RefSeq, Aug 2010]
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