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>   首页   >   产品   >   一抗   >   其他   >   KHSRP Antibody (monoclonal) (M01)   

KHSRP Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant KHSRP.

     
  • 1 - KHSRP Antibody (monoclonal) (M01) AT2608a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (35.53 KDa) .
  • 2 - KHSRP Antibody (monoclonal) (M01) AT2608a
    Immunoperoxidase of monoclonal antibody to KHSRP on formalin-fixed paraffin-embedded human liver. [antibody concentration 3 ug/ml]
  • 3 - KHSRP Antibody (monoclonal) (M01) AT2608a
    Immunofluorescence of monoclonal antibody to KHSRP on HeLa cell . [antibody concentration 10 ug/ml]
  • 10 - KHSRP Antibody (monoclonal) (M01) AT2608a
    Detection limit for recombinant GST tagged KHSRP is approximately 0.3ng/ml as a capture antibody.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC, IF, E
Primary Accession Q92945
Other Accession NM_003685
Reactivity Human
Host mouse
Clonality monoclonal
Isotype IgG2b Kappa
Clone Names 4C10
Calculated MW 73115 Da
Additional Information
Gene ID 8570
Other Names Far upstream element-binding protein 2, FUSE-binding protein 2, KH type-splicing regulatory protein, KSRP, p75, KHSRP, FUBP2
Target/Specificity KHSRP (NP_003676, 151 a.a. ~ 239 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
IHC~~1:100~500
IF~~1:50~200
E~~N/A
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsKHSRP Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

The KHSRP gene encodes a multifunctional RNA-binding protein implicated in a variety of cellular processes, including transcription, alternative pre-mRNA splicing, and mRNA localization (Min et al., 1997 [PubMed 9136930]; Gherzi et al., 2004 [PubMed 15175153]).

REFERENCES

Antagonistic role of hnRNP A1 and KSRP in the regulation of let-7a biogenesis. Michlewski G, et al. Nat Struct Mol Biol, 2010 Aug. PMID 20639884.Dishevelled-KSRP complex regulates Wnt signaling through post-transcriptional stabilization of beta-catenin mRNA. Bikkavilli RK, et al. J Cell Sci, 2010 Apr 15. PMID 20332102.KSRP-PMR1-exosome association determines parathyroid hormone mRNA levels and stability in transfected cells. Nechama M, et al. BMC Cell Biol, 2009 Sep 23. PMID 19775426.Overexpression of far upstream element binding proteins: a mechanism regulating proliferation and migration in liver cancer cells. Malz M, et al. Hepatology, 2009 Oct. PMID 19585652.The RNA-binding protein KSRP promotes the biogenesis of a subset of microRNAs. Trabucchi M, et al. Nature, 2009 Jun 18. PMID 19458619.

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