KIF2C Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant KIF2C.
- 产品详情
- 实验流程
- 背景知识
Application
| WB, IHC, IF, IP, E |
|---|---|
| Primary Accession | Q99661 |
| Other Accession | BC014924 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | monoclonal |
| Isotype | IgG1 kappa |
| Clone Names | 1G2 |
| Calculated MW | 81313 Da |
| Gene ID | 11004 |
|---|---|
| Other Names | Kinesin-like protein KIF2C, Kinesin-like protein 6, Mitotic centromere-associated kinesin, MCAK, KIF2C, KNSL6 |
| Target/Specificity | KIF2C (AAH14924, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 IHC~~1:100~500 IF~~1:50~200 IP~~N/A E~~N/A |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | KIF2C Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
The protein encoded by this gene is a member of kinesin-like protein family. Proteins of this family are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. This protein is important for anaphase chromosome segregation and may be required to coordinate the onset of sister centromere separation.
REFERENCES
1.Mitotic Rounding Alters Cell Geometry to Ensure Efficient Bipolar Spindle Formation.Lancaster OM, Le Berre M, Dimitracopoulos A, Bonazzi D, Zlotek-Zlotkiewicz E, Picone R, Duke T, Piel M, Baum BDev Cell. 2013 May 13;25(3):270-83. doi: 10.1016/j.devcel.2013.03.014. Epub 2013 Apr 25.2.Functional and spatial regulation of the mitotic centromere-associated kinesin by cyclin-dependent kinase 1.Sanhaji M, Friel CT, Kreis NN, Kramer A, Martin C, Howard J, Strebhardt K, Yuan J.Mol Cell Biol. 2010 Apr 5. [Epub ahead of print]
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