癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
RAB11A Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a full length recombinant RAB11A.
- 产品详情
- 实验流程
- 背景知识
Application 
| WB, E |
|---|---|
| Primary Accession | P62491 |
| Other Accession | BC013348 |
| Reactivity | Human, Rat |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG1 kappa |
| Clone Names | 1F7-2A8 |
| Calculated MW | 24394 Da |
| Gene ID | 8766 |
|---|---|
| Other Names | Ras-related protein Rab-11A, Rab-11, YL8, RAB11A, RAB11 |
| Target/Specificity | RAB11A (AAH13348.1, 1 a.a. ~ 216 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 E~~N/A |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | RAB11A Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
The protein encoded by this gene belongs to the small GTPase superfamily, Rab family. It is associated with both constitutive and regulated secretory pathways, and may be involved in protein transport.
REFERENCES
Interaction of the human prostacyclin receptor with Rab11: characterization of a novel Rab11 binding domain within alpha-helix 8 that is regulated by palmitoylation. Reid HM, et al. J Biol Chem, 2010 Jun 11. PMID 20395296.The Rab11 pathway is required for influenza A virus budding and filament formation. Bruce EA, et al. J Virol, 2010 Jun. PMID 20357086.Involvement of Rab9 and Rab11 in the intracellular trafficking of TRPC6. Cayouette S, et al. Biochim Biophys Acta, 2010 Jul. PMID 20346379.Coordination of Rab8 and Rab11 in primary ciliogenesis. Kn?dler A, et al. Proc Natl Acad Sci U S A, 2010 Apr 6. PMID 20308558.Rab11-FIP3 links the Rab11 GTPase and cytoplasmic dynein to mediate transport to the endosomal-recycling compartment. Horgan CP, et al. J Cell Sci, 2010 Jan 15. PMID 20026645.
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